Talks to Watch

Growing Living Rat Neurons To Play... DOOM? | Part 1

4.5M views · Jul 10, 2023 · 27:10 · 3 HN recommenders · 11 mentions · discussed 2023–2026

The Thought Emporium grows living rat neurons on an electrode array and tries to train them to play Doom. It is part of a series on biological computing.

Why Hacker News points people here: Cited whenever biocomputing or neurons-on-chip come up, as an accessible example of how such a system can be built.

“They run an amazing channel that covers a variety of topics. Highly recommend.”HN comment, 2025

What Hacker News said 11

Strongly recommendschneuJun 2025

“They run an amazing channel that covers a variety of topics. Highly recommend.”

Similar neuron project from an amazing channel

Full comment

The YouTuber "The Thought Emporium" has been working on a similar project for a few years. this video They run an amazing channel that covers a variety of topics. Highly recommend. The mummification video is fun.

in “Human Brain Cells on Chip for Sale – First biocomputing platform hits the market” · view on HN
RecommendszonkerdonkerMay 2024

“it os as fascinating and horrifying as it sounds.”

Series training neural network to play DOOM

Full comment

Anyone ineterested in more wetware projects should check out the series from The Thought Emporium on youtube: this video They are attempting to train a (literal) neural network to play DOOM. And yes, it os as fascinating and horrifying as it sounds. It's hard not to extrapolate 50 years down the line with this tech. Stuff gets complicated quick. How many human neurons do you have to use before you get an actual human consiousness?

in “First Bioprocessor Powered by Human Brain Organoids” · view on HN
RecommendsfenykepMar 2026

“the Thought Emporium youtube channel has some explanatory [videos]”

Explains the process of growing neurons that play Doom

Full comment

I think the Thought Emporium youtube channel has some explanatory [videos]( this video ) of the whole process. I couldn't wrap my head around the thing tho.

in “Living Human Brain Cells Play Doom on a CL1” · view on HN
Cites itseesawtronAug 2023

“This paper claims to have found evidence that supports this principle”

Neurons on a chip evidence for free energy principle

Full comment

Karl Friston has been a long time proponent of the free energy principle in brain [0]. This paper claims to have found evidence that supports this principle in "neurons on a chip" based system [1] [0] link [1] this video

in “Mathematical theory predicts self-organized learning in real neurons” · view on HN
Cites itpanarchyDec 2023

Lists Thought Emporium videos on neuron computing

Full comment

this video Growing Living Rat Neurons To Play... DOOM? The Thought Emporium link Growing Human Neurons Connected to a Computer The Thought Emporium

in “'Biocomputer' combines lab-grown brain tissue with electronic hardware” · view on HN
Cites itvinnyvichyAug 2024

“It's conceivable that in the not so far future we will be able to grow computers of our own design”

Full comment

Thank you for your curiosity! Decentralization is a very long term effort -- Grothendieck said it would take generations, we can't expect immediate results. So while 100R certainly can't survive without relying on industry, it does do research into technologies that may be easier to "deindustrialize". See the "off-grid" and "sustainability" pages on their site. Finer point: even before the industrial revolution, humans have had access to supercomputers -- their own brains! It's conceivable that in the not so far future we will be able to grow computers of our own design, from just air and water. See promising efforts in this direction, it's not an empty dream! this video I guess the moral of the day with regards to banks and finance is, don't jump the gun! We will need them until we can grow raspberry pies on a tree!

in “Hundred Rabbits is a small collective exploring the failability of modern tech” · view on HN
Cites ithiatusAug 2024

“Thought Emporium on YouTube made a few videos utilizing organoid bio processors”

Thought Emporium made similar organoid processor videos

Full comment

Thought Emporium on YouTube made a few videos utilizing organoid bio processors but iirc their neuron source is pig not human. this video

in “Human brain organoid bioprocessors now available to rent for $500 per month” · view on HN
Cites itseesawtronAug 2024

“alreadty existing stuff such as neurons playing Doom [0]”

Example of neurons playing Doom

Full comment

I was once contacted by FinalSpark where they offered free early remote access to use their biocomputing platform. The platform is accessible remotely and allows experiments on neurospheres made from living cells, sitting in an incubator, in their lab, in Vevey, Switzerland. A neurosphere is a round structure build out of approximately 10’000 neurons, connected to electrodes in different places. The platform uses python scripts to communicate with the neuron allowing for various functionalities, such as: Stimulate living neurons, Read data from neurons, Log all the data in a database, and Display graphically the results of experiments for further analysis. I was too busy to come up with a clear project idea that could beat alreadty existing stuff such as neurons playing Doom [0] (not related to FinalSpark). Still waiting for someone to show something cool using this platform. [0] this video

in “Human brain organoid bioprocessors now available to rent for $500 per month” · view on HN
Cites itseesawtronAug 2024

Doom neuron project cited as comparison

Full comment

How hard is it to do something like this on your platform [0]? Are there any other real-world examples where people are using your platform to do something similar? [0] this video

in “Human brain organoid bioprocessors now available to rent for $500 per month” · view on HN
Cites itskulkMay 2025

“has some videos that demonstrate how something like this could be built”

Demonstrates how a biological computer could be built

Full comment

The Thought Emporium, a YouTube channel, has some videos that demonstrate how something like this could be built: Growing Rat neurons to play DOOM (unfinished): part 1 -- this video part 2 -- link Growing human neurons: link

in “The CL1: the first code deployable biological computer” · view on HN
JokepreisschildJul 2025

“This reminds me of The Thought Emporium's project of teaching rat brain cells to play doom”

Full comment

> Maybe our first AGI is just a Petri dish brain with a half-decent python API This reminds me of The Thought Emporium's project of teaching rat brain cells to play doom this video

in “I don't think AGI is right around the corner” · view on HN