Talks to Watch

Genetic Engineering and Diseases – Gene Drive & Malaria

9.9M views · Sep 21, 2016 · 7:04 · 1 HN recommender · 3 mentions · discussed 2016–2025

A Kurzgesagt animation on using gene drives to modify mosquitoes against malaria, and whether we should. It explains the mechanism and the ethical trade-offs.

Why Hacker News points people here: HN links it as a clear explainer of gene drive when mosquito genetic engineering comes up.

“one of my favourite Youtube channels”HN comment, 2016

What Hacker News said 3

RecommendssmnscuOct 2016

“one of my favourite Youtube channels”

Similar video on using CRISPR to change mosquito genomes.

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Similar (using crispr to change the mosquitoes' genome) video from Kurzgesagt, one of my favourite Youtube channels: this video

in “We’re trying to stop bad mosquitoes by raising and releasing good ones” · view on HN
Cites itchasilApr 2022

Explains gene drive as a targeted approach against a species.

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The introduction of an invasive species can have an overall beneficial effect if carefully evaluated, and there is a lot that can go wrong. link It appears that a "gene drive" was introduced into the Florida Keys in this case, and that is much more targeted and specific to a species that it is intended to destroy. this video

in “Results from first US trial of genetically modified mosquitoes” · view on HN
Cites itgcanyonMar 2025

“The idea of using gene drive on mosquitoes has been circulating for at least 8 years.”

Background on gene drive mosquitoes circulating for years.

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The idea of using gene drive on mosquitoes has been circulating for at least 8 years. [1] In that time, something like 4 million people have died of malaria, many millions more have been infected, and it is significantly impacting the economic growth of Africa. What will it take for us to pull the trigger on this? 1. this video

in “Gene drive modified mosquitoes offer new tool for malaria elimination efforts” · view on HN