DEF CON 25 - John Sotos - Genetic Diseases to Guide Digital Hacks of the Human Genome

> Messy because it is difficult to limit the damage to targeted enemy combatants. Unfortunately, this may not be true for much longer. See this video for a scare.

That's a terrifying read. See DefCon talk: DEF CON 25 - John Sotos - Genetic Diseases to Guide Digital Hacks of the Human Genome ( this video )

Something even more terrifying to me is illuminated by a talk from John Sotos who served as Chief Medical Officer for Intel. this video "...defensive technology always lags offensive technology. So you know, the cancer moonshot I would propose is dual use, just like nuclear weapons and nuclear power, two sides of the same coin. The ideal cancer treatment someday is going to be the doctors biopsy your tumor, get a sample, send it down to the lab, the lab will figure out the genetic signature of your exact cancer tumor. Then somebody will build a virus, that using that if-then statement, only targets the cancer cells in you. They'll put that virus inside you, you'll feel like you have a cold for a few days, the virus will go to work destroying your cancer, and then you'll wake up cancer free. That's a pretty good deal, we all want that to happen. But notice this exquisite targeting overcomes that big drawback against bioweapons. So the new technologies are going to allow incredibly targeted bioweapons. So think about three different axis. Who might you target?...you could also target a family, like the royal family. You could target a group of people, or an entire species." He goes on to describe examples of what he asserts will be possible to do, which is target virtually any identifiable characteristic among a life form, or cause practically any sort of deficiency or alteration within cells. He also points out that Biotech is currently outpacing Moore's Law, and this technology

this video DEF CON 25 - John Sotos - Genetic Diseases to Guide Digital Hacks of the Human Genome The Chief Medical Officer of Intel says genetic testing in general seems like a terrible security risk one should avoid incurring at all cost. So that's a big fat no.

But if one wanted to, bioengineering ethnic cleansing (or whatever section of genome you're targeting) can be done with a couple thousand dollars worth of supplies in a garage, no nuclear or conventional arsenal required. The point of importance is the barrier to entry is so much lower. DEFCON talk: this video (DEF CON 25 - John Sotos - Genetic Diseases to Guide Digital Hacks of the Human Genome) HN thread: link

I don't have a source per se, just somewhat high level of confidence based on the following (weak, circumstantial) evidence: - There was a lot of bioweapons R&D done in the XX century[0]; it all seems to have been abandoned between the 70s and the 90s, but since the desire for it is not gone, it would be atypical for humanity if it really all ended; - Biological sciences keep progressing; each year, developing bioweapons is easier than it was the year before, and since our control over biological systems grow, so (I believe) the allure of a controlled bioweapon. - You have people like John Sotos - Intel's Chief Medical Officer and a colonel in the Air National Guard - delivering talks like [1], going all serious about the threat of future bioweapons. He seems to think that this is a real danger. - My general tried and true heuristic that if something is within realms of technological feasibility and promises a clear economic or political benefit, it will be attempted, no matter how horrible it is. -- [0] - link [1] - this video

Chief Medical Officer of Intel talking about what hacks look like on people's genetic information. this video

Good. Of course I'm not expecting anyone to prove a negative, but the lab leak theory was dismissed with very little evidence to the contrary. We know other viruses have leaked from labs before [0]. I think part of the resistance to accepting this possibility was that it was strongly associated with Trump supporters. I'm glad people won't be able to use the "that's a Trump supporter theory" bludgeon and we can start hearing experts talk about this in good faith. [0]: this video (thanks to whichever HNer posted this initially - not even sure if it had to do with a covid discussion)

Pandora's box is open, technology will spread regardless of what you do. You want to limit tech that will become cheaper and easier to build through the efforts of legitimate, well meaning research, and try to stop knowledge spreading as we wish for there to be more people in this line of work. More people having access will mean more people who are untrustworthy having access is entirely right but whether "which means more malicious action" is a corollary is up for debate, as we've seen with violent action around the world via many different types of weaponry. In this talk[1] at DEF CON, John Sotos pleads with hackers to put their time into learning how to combat biological weapons. He points out that the tech will move forward to being able to target more and more specific populations. Like any other weapon, knowing that your enemy has it too and can hurt you or those you care about with it is a highly effective deterrent. > As for building your own vaccine. Even large nations were not able to develop effective ones. It’s easier to put a bullet in someone than it is to take it out. Two things here. Firstly, trauma surgery and techniques from the military and places where bullet wounds are common have benefited the rest of us for when we get into scrapes of even a non-violent kind. Secondly, defence does not always lag behind attack, you assume that the future would look like now but that is to ignore the history of any tech of such nature. [1] this video